Endothelin-converting enzyme 1

BE0003793ProteinHumansECE1

Converts big endothelin-1 to endothelin-1. It is acted on by 2 drugs in DrugBank.

Gene name
ECE1
UniProtKB entry
P42892Swiss-Prot
Cellular location
Cell membrane
Residues / weight
770 residues · 87,163 Da
Also known as
3.4.24.71 · ECE-1

Resolves to

Protein
UniProtP42892UniProt nameECE1_HUMAN
Gene
HGNCHGNC:3146NCBI Gene1889GenBank695405GeneCardsECE1
Pharmacology
IUPHAR/GtoPdb1615KEGGhsa:1889
Structure
PDB3DWB
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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22+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Endothelin-converting enzyme 1, and which indications are they being tested in?

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