Aquaporin Z

BE0003818ProteinEscherichia coli (strain K12)aqpZ

Channel that permits osmotically driven movement of water in both directions. It is acted on by 4 drugs in DrugBank.

Gene name
aqpZ
UniProtKB entry
P60844Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
231 residues · 23,703 Da
Also known as
Bacterial nodulin-like intrinsic protein · bniP · Water channel AqpZ

Resolves to

Protein
UniProtP60844UniProt nameAQPZ_ECOLI
Gene
NCBI Gene945497GenBank1051283
Pharmacology
KEGGecj:JW0859
Structure
PDB1RC2PDB2ABMPDB2O9D
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Aquaporin Z, and which indications are they being tested in?

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