Periplasmic oligopeptide-binding protein OppA

BE0003820ProteinSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)oppA

Part of the ABC transporter complex OppABCDF involved in the uptake of oligopeptides, including the cell wall murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate (PubMed:2821267, PubMed:3301822). It is acted on by 1 drug in DrugBank.

Gene name
oppA
UniProtKB entry
P06202Swiss-Prot
Cellular location
Periplasm
Residues / weight
543 residues · 61,292 Da
Also known as
Periplasmic oligopeptide-binding protein

Resolves to

Protein
UniProtP06202UniProt nameOPPA_SALTY
Gene
NCBI Gene1253265GenBank47808
Pharmacology
KEGGstm:STM1746.S
Structure
PDB1B05PDB1B0HPDB1B1H
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Periplasmic oligopeptide-binding protein OppA, and which indications are they being tested in?

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