Cytochrome b-c1 complex subunit 2, mitochondrial

BE0003855ProteinHumansUQCRC2

Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. It is acted on by 8 drugs in DrugBank.

Gene name
UQCRC2
UniProtKB entry
P22695Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
453 residues · 48,443 Da
Also known as
Complex III subunit 2 · Core protein II · Ubiquinol-cytochrome-c reductase complex core protein 2

Resolves to

Protein
UniProtP22695UniProt nameQCR2_HUMAN
Gene
HGNCHGNC:12586NCBI Gene7385GenBank180928GeneCardsUQCRC2
Pharmacology
KEGGhsa:7385
Structure
PDB5XTEPDB5XTHPDB5XTI
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cytochrome b-c1 complex subunit 2, mitochondrial, and which indications are they being tested in?

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