Cytochrome b-c1 complex subunit 6, mitochondrial

BE0003856ProteinHumansUQCRH

Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. It is acted on by 8 drugs in DrugBank.

Gene name
UQCRH
UniProtKB entry
P07919Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
91 residues · 10,739 Da
Also known as
Complex III subunit 6 · Complex III subunit VIII · Cytochrome c1 non-heme 11 kDa protein · Mitochondrial hinge protein · Ubiquinol-cytochrome c reductase complex 11 kDa protein

Resolves to

Protein
UniProtP07919UniProt nameQCR6_HUMAN
Gene
HGNCHGNC:12590NCBI Gene7388GenBank188565GeneCardsUQCRH
Pharmacology
KEGGhsa:7388
Structure
PDB5XTEPDB5XTHPDB5XTI
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cytochrome b-c1 complex subunit 6, mitochondrial, and which indications are they being tested in?

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