Hydroxymycolate synthase MmaA4

BE0003863ProteinMycobacterium tuberculosismmaA4

Involved in the biosynthesis of hydroxymycolate, a common precursor of oxygenated mycolic acids (methoxy-mycolate and keto-mycolate). It is acted on by 1 drug in DrugBank.

Gene name
mmaA4
UniProtKB entry
Q79FX8Swiss-Prot
Residues / weight
301 residues · 34,670 Da
Also known as
2.1.1.- · AdoMet-MT · hma · MA-MT · mma4

Resolves to

Protein
UniProtQ79FX8UniProt nameMMAA4_MYCTU
Gene
NCBI Gene888056GenBank2222772
Pharmacology
KEGGmtu:Rv0642c
Structure
PDB2FK7PDB2FK8PDB3HA3
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
10+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Hydroxymycolate synthase MmaA4, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In