4,4'-diapophytoene synthase

BE0003866ProteinStaphylococcus aureuscrtM

Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress. It is acted on by 4 drugs in DrugBank.

Gene name
crtM
UniProtKB entry
A9JQL9Swiss-Prot
Residues / weight
287 residues · 34,313 Da
Also known as
2.5.1.96 · C30 carotenoid synthase · DAP synthase · Dehydrosqualene synthase · Diapophytoene synthase

Resolves to

Protein
UniProtA9JQL9UniProt nameCRTM_STAAU
Gene
GenBank161788394
Structure
PDB2ZCOPDB2ZCQPDB2ZCR
Drugs

What you can answer from here — as of May 03, 2025

4DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 4,4'-diapophytoene synthase, and which indications are they being tested in?

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