DNA polymerase kappa

BE0003870ProteinHumansPOLK

DNA polymerase specifically involved in DNA repair. It is acted on by 3 drugs in DrugBank.

Gene name
POLK
UniProtKB entry
Q9UBT6Swiss-Prot
Cellular location
Nucleus
Residues / weight
870 residues · 98,808 Da
Also known as
2.7.7.7 · DINB protein · DINB1 · DINP

Resolves to

Protein
UniProtQ9UBT6UniProt namePOLK_HUMAN
Gene
HGNCHGNC:9183NCBI Gene51426GenBank6463740GeneCardsPOLK
Pharmacology
KEGGhsa:51426
Structure
PDB1T94PDB2LSIPDB2OH2
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which compounds in development act on DNA polymerase kappa, and which indications are they being tested in?

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