Peptide deformylase 2

BE0003875ProteinBacillus cereus (strain ATCC 14579 / DSM 31)def2

Removes the formyl group from the N-terminal Met of newly synthesized proteins. It is acted on by 1 drug in DrugBank.

Gene name
def2
UniProtKB entry
Q819K2Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
184 residues · 20,474 Da
Also known as
3.5.1.88 · PDF 2 · Polypeptide deformylase 2

Resolves to

Protein
UniProtQ819K2UniProt nameDEF2_BACCR
Gene
NCBI Gene1206319GenBank29893819
Pharmacology
KEGGbce:BC3974
Structure
PDB2OKL
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Peptide deformylase 2, and which indications are they being tested in?

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