3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

BE0003880ProteinHelicobacter pylori (strain ATCC 700392 / 26695)fabZ

Involved in unsaturated fatty acids biosynthesis. It is acted on by 1 drug in DrugBank.

Gene name
fabZ
UniProtKB entry
O25928Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
159 residues · 18,196 Da
Also known as
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase · (3R)-hydroxymyristoyl-ACP dehydrase · 4.2.1.59 · Beta-hydroxyacyl-ACP dehydratase

Resolves to

Protein
UniProtO25928UniProt nameFABZ_HELPY
Gene
NCBI Gene900307GenBank2313078
Pharmacology
KEGGheo:C694_07100
Structure
PDB2GLLPDB2GLMPDB2GLP
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, and which indications are they being tested in?

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