Cytosol aminopeptidase

BE0003882ProteinHumansLAP3

Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. It is acted on by 3 drugs in DrugBank.

Gene name
LAP3
UniProtKB entry
P28838Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
519 residues · 56,166 Da
Also known as
3.4.11.1 · Cysteinylglycine-S-conjugate dipeptidase · LAP-3 · LAPEP · Leucine aminopeptidase 3

Resolves to

Protein
UniProtP28838UniProt nameAMPL_HUMAN
Gene
HGNCHGNC:18449NCBI Gene51056GenBank4335941GeneCardsLAP3
Pharmacology
KEGGhsa:51056
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cytosol aminopeptidase, and which indications are they being tested in?

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