Myotonin-protein kinase

BE0003890ProteinHumansDMPK

Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. It is acted on by 2 drugs in DrugBank.

Gene name
DMPK
UniProtKB entry
Q09013Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
629 residues · 69,385 Da
Also known as
2.7.11.1 · DM-kinase · DM1 protein kinase · DM1PK · DMK

Resolves to

Protein
UniProtQ09013UniProt nameDMPK_HUMAN
Gene
HGNCHGNC:2933NCBI Gene1760GeneCardsDMPK
Pharmacology
IUPHAR/GtoPdb1505KEGGhsa:1760
Structure
PDB1WT6PDB2VD5
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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15GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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32+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Myotonin-protein kinase, and which indications are they being tested in?

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