Arginine/agmatine antiporter

BE0003904ProteinEscherichia coli O157:H7adiC

Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach (Probable). It is acted on by 1 drug in DrugBank.

Gene name: adiC
UniProtKB entry: P60063Swiss-Prot
Cellular location: Cell inner membrane
Residues / weight: 445 residues · 46,842 Da

Resolves to

Protein

UniProtP60063UniProt nameADIC_ECO57

Gene

NCBI Gene914204GenBank12512676

Pharmacology

KEGGece:Z5717

Structure

PDB3L1LPDB3LRBPDB3LRC

Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action

4GO termsFunction, process and component, as structured annotations

1Pfam domainDomain architecture mapped to Pfam families and clans

4+ReferencesStructured and connected to the statements they support

Which compounds in development act on Arginine/agmatine antiporter, and which indications are they being tested in?

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