Proteasome subunit alpha type-5

BE0003914ProteinHumansPSMA5

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. It is acted on by 1 drug in DrugBank.

Gene name
PSMA5
UniProtKB entry
P28066Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
241 residues · 26,411 Da
Also known as
alpha-5 · Macropain zeta chain · Multicatalytic endopeptidase complex zeta chain · Proteasome subunit alpha-5 · Proteasome zeta chain

Resolves to

Protein
UniProtP28066UniProt namePSA5_HUMAN
Gene
HGNCHGNC:9534NCBI Gene5686GenBank296740GeneCardsPSMA5
Pharmacology
KEGGhsa:5686
Structure
PDB4R3OPDB4R67PDB5A0Q
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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30GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Proteasome subunit alpha type-5, and which indications are they being tested in?

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