Proteasome subunit alpha type-6

BE0003915ProteinHumansPSMA6

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. It is acted on by 1 drug in DrugBank.

Gene name
PSMA6
UniProtKB entry
P60900Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
246 residues · 27,399 Da
Also known as
27 kDa prosomal protein · alpha-1 · Macropain iota chain · Multicatalytic endopeptidase complex iota chain · p27K

Resolves to

Protein
UniProtP60900UniProt namePSA6_HUMAN
Gene
HGNCHGNC:9535NCBI Gene5687GenBank35682GeneCardsPSMA6
Pharmacology
KEGGhsa:5687
Structure
PDB4R3OPDB4R67PDB5A0Q
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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32GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Proteasome subunit alpha type-6, and which indications are they being tested in?

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