Proteasome subunit alpha type-7

BE0003916ProteinHumansPSMA7

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. It is acted on by 2 drugs in DrugBank.

Gene name
PSMA7
UniProtKB entry
O14818Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
248 residues · 27,887 Da
Also known as
alpha-4 · HSPC · Proteasome subunit alpha-4 · Proteasome subunit RC6-1 · Proteasome subunit XAPC7

Resolves to

Protein
UniProtO14818UniProt namePSA7_HUMAN
Gene
HGNCHGNC:9536NCBI Gene5688GenBank2555136GeneCardsPSMA7
Pharmacology
KEGGhsa:5688
Structure
PDB4R3OPDB4R67PDB5A0Q
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1Clinical trialTrials of drugs acting on it, by phase and status
Sign in
24GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
27+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Proteasome subunit alpha type-7, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In