Proteasome subunit beta type-4

BE0003918ProteinHumansPSMB4

Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. It is acted on by 1 drug in DrugBank.

Gene name
PSMB4
UniProtKB entry
P28070Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
264 residues · 29,204 Da
Also known as
26 kDa prosomal protein · beta-7 · HsBPROS26 · HsN3 · Macropain beta chain

Resolves to

Protein
UniProtP28070UniProt namePSB4_HUMAN
Gene
HGNCHGNC:9541NCBI Gene5692GenBank565651GeneCardsPSMB4
Pharmacology
KEGGhsa:5692
Structure
PDB4R3OPDB4R67PDB5A0Q
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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29GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Proteasome subunit beta type-4, and which indications are they being tested in?

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