Proteasome subunit beta type-7

BE0003920ProteinHumansPSMB7

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. It is acted on by 1 drug in DrugBank.

Gene name
PSMB7
UniProtKB entry
Q99436Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
277 residues · 29,965 Da
Also known as
3.4.25.1 · beta-2 · Macropain chain Z · Multicatalytic endopeptidase complex chain Z · Proteasome subunit beta-2

Resolves to

Protein
UniProtQ99436UniProt namePSB7_HUMAN
Gene
HGNCHGNC:9544NCBI Gene5695GenBank1531533GeneCardsPSMB7
Pharmacology
KEGGhsa:5695
Structure
PDB4R3OPDB4R67PDB5A0Q
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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20GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Proteasome subunit beta type-7, and which indications are they being tested in?

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