6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

BE0003931ProteinHumansPFKFB4

Synthesis and degradation of fructose 2,6-bisphosphate. It is acted on by 2 drugs in DrugBank.

Gene name
PFKFB4
UniProtKB entry
Q16877Swiss-Prot
Residues / weight
469 residues · 54,039 Da
Also known as
6PF-2-K/Fru-2,6-P2ase 4 · 6PF-2-K/Fru-2,6-P2ase testis-type isozyme · PFK/FBPase 4

Resolves to

Protein
UniProtQ16877UniProt nameF264_HUMAN
Gene
HGNCHGNC:8875NCBI Gene5210GenBank1905761GeneCardsPFKFB4
Pharmacology
KEGGhsa:5210
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4, and which indications are they being tested in?

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