2'-hydroxybiphenyl-2-sulfinate desulfinase

BE0003956ProteinRhodococcus sp. (strain IGTS8)dszB

Catalyzes the third and final step of the '4S' desulfurization pathway that removes covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. It is acted on by 2 drugs in DrugBank.

Gene name
dszB
UniProtKB entry
P54997Swiss-Prot
Residues / weight
365 residues · 39,044 Da
Also known as
2-(2-hydroxyphenyl)benzenesulfinate desulfinase · 3.13.1.3 · Dibenzothiophene desulfurization enzyme B · dszB · HPBS desulfinase

Resolves to

Protein
UniProtP54997UniProt nameDSZB_RHOSG
Gene
GenBank595291
Structure
PDB2DE2PDB2DE3PDB2DE4
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
4+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on 2'-hydroxybiphenyl-2-sulfinate desulfinase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In