ATP-dependent Clp protease proteolytic subunit

BE0004002ProteinEscherichia coli (strain K12)clpP

Cleaves peptides in various proteins in a process that requires ATP hydrolysis. It is acted on by 1 drug in DrugBank.

Gene name
clpP
UniProtKB entry
P0A6G7Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
207 residues · 23,186 Da
Also known as
3.4.21.92 · Caseinolytic protease · Endopeptidase Clp · Heat shock protein F21.5 · lopP

Resolves to

Protein
UniProtP0A6G7UniProt nameCLPP_ECOLI
Gene
NCBI Gene945082GenBank145555
Pharmacology
KEGGecj:JW0427
Structure
PDB1TYFPDB1YG6PDB1YG8
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which compounds in development act on ATP-dependent Clp protease proteolytic subunit, and which indications are they being tested in?

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