Urease subunit beta
Details
- Name
- Urease subunit beta
- Kind
- protein
- Synonyms
- 3.5.1.5
- Urea amidohydrolase subunit beta
- Gene Name
- ureB
- UniProtKB Entry
- P41021Swiss-Prot
- Organism
- Sporosarcina pasteurii
- NCBI Taxonomy ID
- 1474
- Amino acid sequence
>lcl|BSEQ0012795|Urease subunit beta MSNNNYIVPGEYRVAEGEIEINAGREKTTIRVSNTGDRPIQVGSHIHFVEVNKELLFDRA EGIGRRLNIPSGTAARFEPGEEMEVELTELGGNREVFGISDLTNGSVDNKELILQRAKEL GYKGVE
- Number of residues
- 126
- Molecular Weight
- 13958.485
- Theoretical pI
- 4.61
- GO Classification
- Functionsurease activityProcessesurea catabolic processComponentscytoplasm
- General Function
- Not Available
- Specific Function
- urease activity
- Pfam Domain Function
- Urease_beta (PF00699)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0007664|303 bp ATGCATTTAAATCCAGCAGAGAAAGAAAAATTACAAATTTTTCTAGCGAGCGAATTACTC TTAAGGCGTAAAGCAAGAGGTCTTAAGTTGAACTATCCGGAAGCAGTTGCGATCATCACA AGTTTCATTATGGAGGGTGCGCGTGACGGAAAGACGGTAGCGATGCTAATGGAAGAAGGA AAACACGTTCTTACGAGGGACGATGTTATGGAAGGTGTACCAGAAATGATTGATGATATT CAAGCAGAAGCTACTTTCCCGGATGGAACTAAACTCGTAACTGTTCACAATCCAATTTCT TAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P41021 UniProtKB Entry Name URE2_SPOPA GenBank Protein ID 498709 GenBank Gene ID X78411 PDB ID(s) 1IE7, 1S3T, 1UBP, 2UBP, 3UBP, 4AC7, 4CEU, 4CEX, 4UBP - General References
- Benini S, Ciurli S, Nolting HF, Mangani S: X-ray absorption spectroscopy study of native and phenylphosphorodiamidate-inhibited Bacillus pasteurii urease. Eur J Biochem. 1996 Jul 1;239(1):61-6. [Article]
- Benini S, Ciurli S, Rypniewski WR, Wilson KS, Mangani S: Crystallization and preliminary high-resolution X-ray diffraction analysis of native and beta-mercaptoethanol-inhibited urease from Bacillus pasteurii. Acta Crystallogr D Biol Crystallogr. 1998 May 1;54(Pt 3):409-12. [Article]
- Benini S, Rypniewski WR, Wilson KS, Miletti S, Ciurli S, Mangani S: A new proposal for urease mechanism based on the crystal structures of the native and inhibited enzyme from Bacillus pasteurii: why urea hydrolysis costs two nickels. Structure. 1999 Feb 15;7(2):205-16. [Article]
- Benini S, Rypniewski WR, Wilson KS, Miletti S, Ciurli S, Mangani S: The complex of Bacillus pasteurii urease with acetohydroxamate anion from X-ray data at 1.55 A resolution. J Biol Inorg Chem. 2000 Feb;5(1):110-8. [Article]
- Benini S, Rypniewski WR, Wilson KS, Ciurli S, Mangani S: Structure-based rationalization of urease inhibition by phosphate: novel insights into the enzyme mechanism. J Biol Inorg Chem. 2001 Oct;6(8):778-90. [Article]
- Benini S, Rypniewski WR, Wilson KS, Mangani S, Ciurli S: Molecular details of urease inhibition by boric acid: insights into the catalytic mechanism. J Am Chem Soc. 2004 Mar 31;126(12):3714-5. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details N-Carboxymethionine experimental unknown target Details