Ribosomal RNA small subunit methyltransferase F

BE0004011ProteinThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)rsmF

Specifically methylates the cytosines at positions 1400 (m5C1400), 1404 (m5C1404) and 1407 (m5C1407) of 16S rRNA. It is acted on by 1 drug in DrugBank.

Gene name
rsmF
UniProtKB entry
Q5SII2Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
456 residues · 49,739 Da
Also known as
2.1.1.- · rRNA (cytosine-C(5)-)-methyltransferase RsmF

Resolves to

Protein
UniProtQ5SII2UniProt nameRSMF_THET8
Gene
NCBI Gene3168094GenBank55771383
Pharmacology
KEGGttj:TTHA1387
Structure
PDB3M6UPDB3M6VPDB3M6W
Drugs

What you can answer from here — as of September 04, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Ribosomal RNA small subunit methyltransferase F, and which indications are they being tested in?

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