Ribonuclease H

BE0004032ProteinBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)rnhA

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. It is acted on by 1 drug in DrugBank.

Gene name
rnhA
UniProtKB entry
Q9KEI9Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
196 residues · 22,373 Da
Also known as
3.1.26.4 · RNase H

Resolves to

Protein
UniProtQ9KEI9UniProt nameRNH1_HALH5
Gene
GenBank10172613
Pharmacology
KEGGbha:BH0863
Structure
PDB1ZBFPDB1ZBIPDB1ZBL
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
3+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Ribonuclease H, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In