Tyrosine ammonia-lyase

BE0004033ProteinRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)hutH

Catalyzes the non-oxidative deamination of L-tyrosine. It is acted on by 2 drugs in DrugBank.

Gene name
hutH
UniProtKB entry
Q3IWB0Swiss-Prot
Residues / weight
523 residues · 54,913 Da
Also known as
4.3.1.23

Resolves to

Protein
UniProtQ3IWB0UniProt nameTALY_CERS4
Gene
NCBI Gene3722088GenBank77389407
Pharmacology
KEGGrsp:RSP_3574
Structure
PDB2O6YPDB2O78PDB2O7B
Drugs

What you can answer from here — as of September 04, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Tyrosine ammonia-lyase, and which indications are they being tested in?

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