Octanoyltransferase

BE0004039ProteinMycobacterium tuberculosislipB

Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. It is acted on by 1 drug in DrugBank.

Gene name
lipB
UniProtKB entry
P9WK83Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
230 residues · 24,210 Da
Also known as
2.3.1.181 · Lipoate-protein ligase B · Lipoyl/octanoyl transferase · Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase

Resolves to

Protein
UniProtP9WK83UniProt nameLIPB_MYCTU
Gene
NCBI Gene887626
Pharmacology
KEGGmtu:Rv2217
Structure
PDB1W66
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Octanoyltransferase, and which indications are they being tested in?

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