Fumarate reductase flavoprotein subunit

BE0004046ProteinWolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)frdA

The fumarate reductase enzyme complex is required for fumarate respiration using formate or sulfide as electron donor. It is acted on by 1 drug in DrugBank.

Gene name
frdA
UniProtKB entry
P17412Swiss-Prot
Residues / weight
656 residues · 72,718 Da
Also known as
1.3.5.1 · 1.3.5.4 · QFR flavoprotein subunit · Quinol-fumarate reductase flavoprotein subunit

Resolves to

Protein
UniProtP17412UniProt nameFRDA_WOLSU
Gene
GenBank2281995
Pharmacology
KEGGwsu:WS0831
Structure
PDB1E7PPDB1QLBPDB2BS2
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Fumarate reductase flavoprotein subunit, and which indications are they being tested in?

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