Fumarate reductase iron-sulfur subunit

BE0004047ProteinWolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)frdB

The fumarate reductase enzyme complex is required for fumarate respiration using formate or sulfide as electron donor. It is acted on by 1 drug in DrugBank.

Gene name
frdB
UniProtKB entry
P17596Swiss-Prot
Residues / weight
239 residues · 27,165 Da
Also known as
1.3.5.1 · QFR iron-sulfur subunit · Quinol-fumarate reductase iron-sulfur subunit

Resolves to

Protein
UniProtP17596UniProt nameFRDB_WOLSU
Gene
GenBank2281995
Pharmacology
KEGGwsu:WS0830
Structure
PDB1E7PPDB1QLBPDB2BS2
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Fumarate reductase iron-sulfur subunit, and which indications are they being tested in?

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