Tryptophan synthase alpha chain

BE0004065ProteinSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)trpA

The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. It is acted on by 12 drugs in DrugBank.

Gene name
trpA
UniProtKB entry
P00929Swiss-Prot
Residues / weight
268 residues · 28,670 Da
Also known as
4.2.1.20

Resolves to

Protein
UniProtP00929UniProt nameTRPA_SALTY
Gene
NCBI Gene1253246GenBank47939
Pharmacology
KEGGstm:STM1727
Structure
PDB1A50PDB1A5APDB1A5B
Drugs

What you can answer from here — as of September 07, 2019

12DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1GO termFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
22+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Tryptophan synthase alpha chain, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In