Neocarzinostatin

BE0004080ProteinStreptomyces carzinostaticusncsA

NCS has antibiotic activity (for Gram-positive bacteria) and antitumor activity (for certain mouse tumors). It is acted on by 3 drugs in DrugBank.

Gene name
ncsA
UniProtKB entry
P0A3R9Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
147 residues · 14,455 Da
Also known as
Mitomalcin · MMC · NCS

Resolves to

Protein
UniProtP0A3R9UniProt nameNCZS_STRCZ
Gene
GenBank398596
Structure
PDB1J5HPDB1J5IPDB1NCO
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Neocarzinostatin, how selective are they, and which programs against it are still in active trials?

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