2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

BE0004091ProteinShewanella oneidensis (strain MR-1)ispF

Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. It is acted on by 1 drug in DrugBank.

Gene name
ispF
UniProtKB entry
Q8EBR3Swiss-Prot
Residues / weight
159 residues · 16,995 Da
Also known as
4.6.1.12 · MECDP-synthase

Resolves to

Protein
UniProtQ8EBR3UniProt nameISPF_SHEON
Gene
NCBI Gene1171112GenBank24345351
Pharmacology
KEGGson:SO_3437
Structure
PDB1T0A
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
3+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In