Platelet-activating factor acetylhydrolase IB subunit alpha1

BE0004103ProteinHumansPAFAH1B3

Alpha1 catalytic subunit of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)) heterotetrameric enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and modulates... It is acted on by 1 drug in DrugBank.

Gene name
PAFAH1B3
UniProtKB entry
Q15102Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
231 residues · 25,734 Da
Also known as
3.1.1.47 · PAF acetylhydrolase 29 kDa subunit · PAF-AH 29 kDa subunit · PAF-AH subunit gamma · PAFAH subunit gamma

Resolves to

Protein
UniProtQ15102UniProt namePA1B3_HUMAN
Gene
HGNCHGNC:8576NCBI Gene5050GenBank1122219GeneCardsPAFAH1B3
Pharmacology
KEGGhsa:5050
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Platelet-activating factor acetylhydrolase IB subunit alpha1, and which indications are they being tested in?

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