Methionine aminopeptidase 1

BE0004117ProteinHumansMETAP1

Cotranslationally removes the N-terminal methionine from nascent proteins. It is acted on by 4 drugs in DrugBank.

Gene name
METAP1
UniProtKB entry
P53582Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
386 residues · 43,215 Da
Also known as
3.4.11.18 · KIAA0094 · MAP 1 · MetAP 1 · Peptidase M 1

Resolves to

Protein
UniProtP53582UniProt nameMAP11_HUMAN
Gene
HGNCHGNC:15789NCBI Gene23173GenBank577315GeneCardsMETAP1
Pharmacology
IUPHAR/GtoPdb1572KEGGhsa:23173
Structure
PDB2B3HPDB2B3KPDB2B3L
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Methionine aminopeptidase 1, and which indications are they being tested in?

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