Formate dehydrogenase, nitrate-inducible, major subunit

BE0004126ProteinEscherichia coli (strain K12)fdnG

Formate dehydrogenase allows E.coli to use formate as major electron donor during anaerobic respiration, when nitrate is used as electron acceptor. It is acted on by 1 drug in DrugBank.

Gene name
fdnG
UniProtKB entry
P24183Swiss-Prot
Cellular location
Periplasm
Residues / weight
1,015 residues · 112,963 Da
Also known as
1.1.5.6 · 1.17.5.3 · Anaerobic formate dehydrogenase major subunit · FDH-N subunit alpha · Formate dehydrogenase-N subunit alpha

Resolves to

Protein
UniProtP24183UniProt nameFDNG_ECOLI
Gene
NCBI Gene946035
Pharmacology
KEGGecj:JW1470
Structure
PDB1KQFPDB1KQG
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Formate dehydrogenase, nitrate-inducible, major subunit, and which indications are they being tested in?

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