Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit

BE0004127ProteinEscherichia coli (strain K12)fdnH

Formate dehydrogenase allows E.coli to use formate as major electron donor during anaerobic respiration, when nitrate is used as electron acceptor. It is acted on by 1 drug in DrugBank.

Gene name
fdnH
UniProtKB entry
P0AAJ3Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
294 residues · 32,238 Da
Also known as
Anaerobic formate dehydrogenase iron-sulfur subunit · FDH-N subunit beta · Formate dehydrogenase-N subunit beta

Resolves to

Protein
UniProtP0AAJ3UniProt nameFDNH_ECOLI
Gene
NCBI Gene948794
Pharmacology
KEGGecj:JW1471
Structure
PDB1KQFPDB1KQG
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit, and which indications are they being tested in?

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