Biotin biosynthesis cytochrome P450

BE0004134ProteinBacillus subtilis (strain 168)bioI

Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It is acted on by 1 drug in DrugBank.

Gene name
bioI
UniProtKB entry
P53554Swiss-Prot
Residues / weight
395 residues · 44,865 Da
Also known as
1.14.14.46 · 1.14.15.12 · CYP107H

Resolves to

Protein
UniProtP53554UniProt nameBIOI_BACSU
Gene
NCBI Gene935928GenBank1277025
Pharmacology
KEGGbsu:BSU30190
Structure
PDB3EJBPDB3EJDPDB3EJE
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Biotin biosynthesis cytochrome P450, and which indications are they being tested in?

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