Calpain small subunit 1

BE0004144ProteinHumansCAPNS1

Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. It is acted on by 1 drug in DrugBank.

Gene name
CAPNS1
UniProtKB entry
P04632Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
268 residues · 28,316 Da
Also known as
Calcium-activated neutral proteinase small subunit · Calcium-dependent protease small subunit · Calcium-dependent protease small subunit 1 · Calpain regulatory subunit · CANP small subunit

Resolves to

Protein
UniProtP04632UniProt nameCPNS1_HUMAN
Gene
HGNCHGNC:1481NCBI Gene826GenBank35328GeneCardsCAPNS1
Pharmacology
KEGGhsa:826
Structure
PDB1KFUPDB1KFXPDB4PHJ
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Calpain small subunit 1, and which indications are they being tested in?

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