Kallikrein-7

BE0004150ProteinHumansKLK7

May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. It is acted on by 2 drugs in DrugBank.

Gene name
KLK7
UniProtKB entry
P49862Swiss-Prot
Cellular location
Secreted
Residues / weight
253 residues · 27,525 Da
Also known as
3.4.21.117 · hK7 · hSCCE · PRSS6 · SCCE

Resolves to

Protein
UniProtP49862UniProt nameKLK7_HUMAN
Gene
HGNCHGNC:6368NCBI Gene5650GenBank532504GeneCardsKLK7
Pharmacology
IUPHAR/GtoPdb2377KEGGhsa:5650
Structure
PDB2QXGPDB2QXHPDB2QXI
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Kallikrein-7, and which indications are they being tested in?

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