Protein spire homolog 2

BE0004157ProteinHumansSPIRE2

Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament (PubMed:21620703). It is acted on by 1 drug in DrugBank.

Gene name
SPIRE2
UniProtKB entry
Q8WWL2Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
714 residues · 79,670 Da
Also known as
KIAA1832 · Spir-2 · SPIR2

Resolves to

Protein
UniProtQ8WWL2UniProt nameSPIR2_HUMAN
Gene
HGNCHGNC:30623NCBI Gene84501GenBank17932848GeneCardsSPIRE2
Pharmacology
KEGGhsa:84501
Structure
PDB5JCY
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Protein spire homolog 2, and which indications are they being tested in?

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