Peptidyl-prolyl cis-trans isomerase A

BE0004194ProteinEscherichia coli (strain K12)ppiA

PPIases accelerate the folding of proteins (Probable). It is acted on by 1 drug in DrugBank.

Gene name
ppiA
UniProtKB entry
P0AFL3Swiss-Prot
Cellular location
Periplasm
Residues / weight
190 residues · 20,431 Da
Also known as
5.2.1.8 · Cyclophilin A · PPIase A · rot · rotA

Resolves to

Protein
UniProtP0AFL3UniProt namePPIA_ECOLI
Gene
NCBI Gene947870GenBank145287
Pharmacology
KEGGecj:JW3326
Structure
PDB1CLHPDB1J2APDB1V9T
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Peptidyl-prolyl cis-trans isomerase A, and which indications are they being tested in?

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