30S ribosomal protein S2
Details
- Name
- 30S ribosomal protein S2
- Kind
- protein
- Synonyms
- rps2
- Gene Name
- rpsB
- UniProtKB Entry
- P80371Swiss-Prot
- Organism
- Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
- NCBI Taxonomy ID
- 300852
- Amino acid sequence
>lcl|BSEQ0017372|30S ribosomal protein S2 MPVEITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIED LAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEA LFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKL FIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ EAEATETPEGESEVEA
- Number of residues
- 256
- Molecular Weight
- 29276.395
- Theoretical pI
- 5.3
- GO Classification
- FunctionsrRNA binding / structural constituent of ribosomeProcessestranslationComponentssmall ribosomal subunit
- General Function
- Spans the head-body hinge region of the 30S subunit. Is loosely associated with the 30S subunit.
- Specific Function
- rRNA binding
- Pfam Domain Function
- Ribosomal_S2 (PF00318)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0017373|30S ribosomal protein S2 (rpsB) ATGCCCGTAGAGATCACGGTTAAGGAGCTCCTGGAAGCCGGTGTCCACTTCGGCCACGAG AGGAAGCGCTGGAACCCCAAGTTCGCCCGCTACATCTACGCGGAGCGGAACGGCATCCAC ATCATTGACCTCCAGAAGACCATGGAGGAGCTGGAGCGCACGTTCCGCTTCATTGAGGAC CTGGCCATGCGCGGCGGGACGATCCTCTTCGTGGGGACCAAGAAGCAGGCCCAGGACATC GTGCGCATGGAGGCGGAGCGTGCGGGCATGCCCTATGTGAACCAGCGCTGGCTCGGCGGC ATGCTCACCAACTTCAAGACCATCTCCCAGCGGGTCCACCGGCTGGAGGAGCTGGAGGCC CTCTTCGCCTCCCCGGAGATTGAGGAGCGCCCCAAGAAGGAGCAGGTCCGGCTGAAGCAC GAGCTGGAACGGCTTCAGAAGTACCTCTCCGGCTTCCGCCTCCTGAAGCGCCTCCCCGAC GCCATCTTCGTCGTGGATCCGACCAAGGAGGCCATCGCCGTCCGGGAGGCGAGGAAGCTC TTCATCCCCGTGATCGCCCTGGCGGACACGGACTCCGACCCCGACCTGGTGGACTACATC ATCCCCGGCAACGACGACGCCATCCGCTCCATCCAGCTCATCCTCTCCCGGGCGGTGGAC CTCATCATCCAGGCCCGGGGCGGGGTGGTGGAGCCCTCCCCCTCCTACGCCCTGGTGCAG GAGGCGGAAGCCACCGAGACGCCCGAGGGCGAAAGCGAGGTGGAAGCATGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
- General References
- Tsiboli P, Herfurth E, Choli T: Purification and characterization of the 30S ribosomal proteins from the bacterium Thermus thermophilus. Eur J Biochem. 1994 Nov 15;226(1):169-77. [Article]
- Blank J, Nock S, Kreutzer R, Sprinzl M: Elongation factor Ts from Thermus thermophilus-- overproduction in Escherichia coli, quaternary structure and interaction with elongation factor Tu. Eur J Biochem. 1996 Feb 15;236(1):222-7. [Article]
- Wimberly BT, Brodersen DE, Clemons WM Jr, Morgan-Warren RJ, Carter AP, Vonrhein C, Hartsch T, Ramakrishnan V: Structure of the 30S ribosomal subunit. Nature. 2000 Sep 21;407(6802):327-39. [Article]
- Schluenzen F, Tocilj A, Zarivach R, Harms J, Gluehmann M, Janell D, Bashan A, Bartels H, Agmon I, Franceschi F, Yonath A: Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution. Cell. 2000 Sep 1;102(5):615-23. [Article]
- Brodersen DE, Clemons WM Jr, Carter AP, Morgan-Warren RJ, Wimberly BT, Ramakrishnan V: The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. Cell. 2000 Dec 22;103(7):1143-54. [Article]
- Carter AP, Clemons WM, Brodersen DE, Morgan-Warren RJ, Wimberly BT, Ramakrishnan V: Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature. 2000 Sep 21;407(6802):340-8. [Article]
- Yusupova GZ, Yusupov MM, Cate JH, Noller HF: The path of messenger RNA through the ribosome. Cell. 2001 Jul 27;106(2):233-41. [Article]
- Pioletti M, Schlunzen F, Harms J, Zarivach R, Gluhmann M, Avila H, Bashan A, Bartels H, Auerbach T, Jacobi C, Hartsch T, Yonath A, Franceschi F: Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3. EMBO J. 2001 Apr 17;20(8):1829-39. [Article]
- Carter AP, Clemons WM Jr, Brodersen DE, Morgan-Warren RJ, Hartsch T, Wimberly BT, Ramakrishnan V: Crystal structure of an initiation factor bound to the 30S ribosomal subunit. Science. 2001 Jan 19;291(5503):498-501. [Article]
- Yusupov MM, Yusupova GZ, Baucom A, Lieberman K, Earnest TN, Cate JH, Noller HF: Crystal structure of the ribosome at 5.5 A resolution. Science. 2001 May 4;292(5518):883-96. Epub 2001 Mar 29. [Article]
- Ogle JM, Brodersen DE, Clemons WM Jr, Tarry MJ, Carter AP, Ramakrishnan V: Recognition of cognate transfer RNA by the 30S ribosomal subunit. Science. 2001 May 4;292(5518):897-902. [Article]
- Brodersen DE, Clemons WM Jr, Carter AP, Wimberly BT, Ramakrishnan V: Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 S RNA. J Mol Biol. 2002 Feb 22;316(3):725-68. [Article]
- Sharma MR, Barat C, Wilson DN, Booth TM, Kawazoe M, Hori-Takemoto C, Shirouzu M, Yokoyama S, Fucini P, Agrawal RK: Interaction of Era with the 30S ribosomal subunit implications for 30S subunit assembly. Mol Cell. 2005 Apr 29;18(3):319-29. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details 2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE experimental unknown target Details