FMN-dependent NAD(P)H:quinone oxidoreductase 1

BE0004222ProteinPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)azoR1

Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones (PubMed:24915188). It is acted on by 1 drug in DrugBank.

Gene name
azoR1
UniProtKB entry
Q9I5F3Swiss-Prot
Residues / weight
212 residues · 23,050 Da
Also known as
1.6.5.- · 1.7.-.- · Azo-dye reductase 1 · FMN-dependent NADH-azo compound oxidoreductase 1 · FMN-dependent NADH-azoreductase 1

Resolves to

Protein
UniProtQ9I5F3UniProt nameAZOR1_PSEAE
Gene
NCBI Gene882036GenBank9945819
Pharmacology
KEGGpae:PA0785
Structure
PDB2V9CPDB3KEGPDB3LT5
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on FMN-dependent NAD(P)H:quinone oxidoreductase 1, and which indications are they being tested in?

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