Enoyl-CoA delta isomerase 2

BE0004233ProteinHumansECI2

Auxiliary enzyme in the beta-oxidation of mono- and polyunsaturated fatty acids (PubMed:10419495). It is acted on by 1 drug in DrugBank.

Gene name
ECI2
UniProtKB entry
O75521Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
394 residues · 43,585 Da
Also known as
5.3.3.8 · D3,D2-enoyl-CoA isomerase · DBI-related protein 1 · Delta(3),delta(2)-enoyl-CoA isomerase · Diazepam-binding inhibitor-related protein 1

Resolves to

Protein
UniProtO75521UniProt nameECI2_HUMAN
Gene
HGNCHGNC:14601NCBI Gene10455GenBank3193336GeneCardsECI2
Pharmacology
KEGGhsa:10455
Structure
PDB2CQUPDB2F6QPDB4U18
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Enoyl-CoA delta isomerase 2, and which indications are they being tested in?

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