Protein Nef

BE0004237ProteinHIV-1nef

Factor of infectivity and pathogenicity, required for optimal virus replication. It is acted on by 1 drug in DrugBank.

Gene name
nef
UniProtKB entry
P04324Swiss-Prot
Cellular location
Host cell membrane
Residues / weight
206 residues · 23,366 Da
Also known as
3'ORF · F-protein · Negative factor

Resolves to

Protein
UniProtP04324UniProt nameNEF_HV112
Structure
PDB1QA4PDB1QA5PDB1ZEC
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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24GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Protein Nef, and which indications are they being tested in?

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