Alpha-pyrone synthesis polyketide synthase-like Pks18

BE0004239ProteinMycobacterium tuberculosispks18

Involved in the biosynthesis of tri- and tetraketide alpha-pyrones. It is acted on by 1 drug in DrugBank.

Gene name
pks18
UniProtKB entry
P9WPF1Swiss-Prot
Residues / weight
393 residues · 42,032 Da
Also known as
2.3.1.- · Alpha-pyrone synthesis polyketide synthase type III Pks18 · Chalcone synthase-like protein · CHS-like

Resolves to

Protein
UniProtP9WPF1UniProt namePKS18_MYCTU
Gene
NCBI Gene886797
Pharmacology
KEGGmtu:Rv1372
Structure
PDB1TEDPDB1TEE
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Alpha-pyrone synthesis polyketide synthase-like Pks18, and which indications are they being tested in?

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