Actin-related protein 3

BE0004251ProteinHumansACTR3

ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9000076). It is acted on by 2 drugs in DrugBank.

Gene name
ACTR3
UniProtKB entry
P61158Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
418 residues · 47,371 Da
Also known as
Actin-like protein 3 · ARP3

Resolves to

Protein
UniProtP61158UniProt nameARP3_HUMAN
Gene
HGNCHGNC:170NCBI Gene10096GenBank2282032GeneCardsACTR3
Pharmacology
KEGGhsa:10096
Structure
PDB6UHCPDB6YW6PDB6YW7
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
7GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
17+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Actin-related protein 3, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In