Naphthalene 1,2-dioxygenase system, small oxygenase component

BE0004260ProteinPseudomonas putidandoC

Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene. It is acted on by 1 drug in DrugBank.

Gene name
ndoC
UniProtKB entry
P0A112Swiss-Prot
Residues / weight
194 residues · 22,935 Da
Also known as
1.14.12.12 · nahAD · Naphthalene 1,2-dioxygenase ISP beta · Naphthalene 1,2-dioxygenase subunit beta · ND subunit beta

Resolves to

Protein
UniProtP0A112UniProt nameNDOC_PSEPU
Gene
NCBI Gene1343188GenBank151393
Pharmacology
KEGGpg:1343188
Structure
PDB1EG9PDB1NDOPDB1O7G
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Naphthalene 1,2-dioxygenase system, small oxygenase component, and which indications are they being tested in?

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