Immunoglobulin heavy variable 1-2

BE0004264ProteinHumansIGHV1-2

V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). It is acted on by 3 drugs in DrugBank.

Gene name
IGHV1-2
UniProtKB entry
P23083Swiss-Prot
Cellular location
Secreted
Residues / weight
117 residues · 13,085 Da
Also known as
Ig heavy chain V-I region ND · Ig heavy chain V-I region V35

Resolves to

Protein
UniProtP23083UniProt nameHV102_HUMAN
Gene
HGNCHGNC:5550GeneCardsIGHV1-2
Structure
PDB1WT5
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Immunoglobulin heavy variable 1-2, and which indications are they being tested in?

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