Transcriptional activator protein LasR

BE0004269ProteinPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)lasR

Transcriptional activator of elastase structural gene (LasB). It is acted on by 1 drug in DrugBank.

Gene name
lasR
UniProtKB entry
P25084Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
239 residues · 26,618 Da

Resolves to

Protein
UniProtP25084UniProt nameLASR_PSEAE
Gene
NCBI Gene881789GenBank151326
Pharmacology
KEGGpae:PA1430
Structure
PDB2UV0PDB3IX3PDB3IX4
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Transcriptional activator protein LasR, and which indications are they being tested in?

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