Long-chain-fatty-acid--CoA ligase ACSBG1

BE0004272ProteinHumansACSBG1

Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:10954726, PubMed:12975357, PubMed:24269233). It is acted on by 1 drug in DrugBank.

Gene name
ACSBG1
UniProtKB entry
Q96GR2Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
724 residues · 81,290 Da
Also known as
6.2.1.3 · Acyl-CoA synthetase bubblegum family member 1 · BGM · hBG1 · hsBG

Resolves to

Protein
UniProtQ96GR2UniProt nameACBG1_HUMAN
Gene
HGNCHGNC:29567NCBI Gene23205GenBank9957538GeneCardsACSBG1
Pharmacology
KEGGhsa:23205
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Long-chain-fatty-acid--CoA ligase ACSBG1, and which indications are they being tested in?

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